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Better Living Through Well Being

A new report from the Center for Sustainable Economy (CSE) highlights the severe environmental and economic consequences of clearcutting boreal forests in Ontario, Canada, for the production of toilet paper and paper towels sold in the United States. The report estimates that over 3.8 million tons of carbon pollution are generated annually from this practice, equivalent to emissions from more than 824,000 gas-powered vehicles. The resulting economic damages exceed $560 million per year, effectively canceling out any financial gains from pulp exports. Despite this, Canada and the US have failed to incorporate the true environmental costs into their trade and environmental policies.

The report urges policymakers to adopt reforms such as border carbon adjustments (BCAs) to incentivize the production and use of non-wood alternatives like hemp, bamboo, and agricultural waste. Advocates, including CSE and the Environmental Paper Network, argue that the current system unfairly subsidizes timber-based industries at the expense of the climate and public interest. They call for policy changes that support sustainable alternatives and reflect the real cost of environmental degradation, hoping that governments and consumers will push for ethical and eco-friendly reforms in the paper industry.

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A recent study published in the Journal of Alzheimer’s Disease highlights how Linus Health's digital platform can detect early signs of cognitive decline far sooner than traditional methods. Using a 7-minute, speech-based digital assessment, the platform measures not just test answers, but the response time (latency) between prompts and answers -- revealing subtle neurological changes that may indicate emerging cognitive impairment, even when responses are correct. This approach, rooted in the Boston Process Approach, introduces novel digital biomarkers and offers a scalable, efficient tool for early detection of conditions like mild cognitive impairment and Alzheimer’s disease.

Researchers argue that Linus Health’s precision neurocognition technology could replace hours of traditional testing, offering clinicians a more efficient, accurate, and earlier way to assess brain health during routine visits. Powered by AI and high-resolution data analysis, this innovation supports timely diagnosis, enabling earlier intervention and improving outcomes for aging populations at risk of neurodegenerative diseases.

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A groundbreaking study led by researchers from NYU Langone Health and collaborators in China has introduced a novel treatment strategy for autoimmune diseases like Type 1 diabetes, hepatitis, and multiple sclerosis. The research, published in Cell, shows that a specially engineered bispecific antibody -- called BiTS -- can precisely shut down the immune system’s rogue T cells without broadly suppressing immunity. By holding together two key protein complexes (TCR and LAG-3) on the surface of T cells, the treatment prevents autoimmune attacks on healthy tissues in mice, while minimizing the risks typically associated with immune suppression.

The approach hinges on new insights into how LAG-3, an immune checkpoint protein, suppresses T cell activity when in close proximity to the T cell receptor (TCR). BiTS enforces this proximity more effectively than natural processes, offering targeted immune regulation. The therapy successfully reduced tissue damage in mouse models of diabetes, hepatitis, and multiple sclerosis. The findings pave the way for more spatially guided immunotherapies, potentially transforming treatment for a range of autoimmune conditions with fewer side effects than current methods.

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A new nasal COVID-19 vaccine, CVXGA, has shown promising results in a U.S.-based Phase 1 clinical trial led by Cincinnati Children's Hospital. The trial found that a single nasal dose was safe, well-tolerated, and capable of generating strong immune responses both in the nasal mucosa and systemically. Participants receiving higher doses experienced significantly lower rates of symptomatic infection, with infection rates dropping to as low as 11.1%, compared to 73.3% in the low-dose group. Mild side effects such as runny nose and nausea were reported, but no serious adverse effects occurred.

The vaccine, developed by CyanVac LLC, could offer advantages over traditional injected vaccines by directly targeting the virus at its entry point -- nasal tissues -- potentially preventing transmission more effectively. With COVID-19 still causing hundreds of deaths monthly, especially in the U.S., researchers see nasal vaccines as a crucial next step. Based on these initial results, two larger clinical trials are now underway, including one aiming to enroll over 10,000 participants by 2026, to confirm the vaccine’s effectiveness on a broader scale.

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A recent survey conducted by Horowitz Research reveals that 91% of homeowners in California, Texas, and Florida are deeply concerned about extreme weather, rising energy bills, and grid instability. Many expressed dissatisfaction with existing solar energy solutions and a strong interest in more reliable backup power options. Over 70% of respondents either own or want to own solar battery systems, and 60% are seeking greater independence from the power grid. These concerns are especially urgent in states frequently impacted by climate-related disasters and infrastructure failures.

In response to this growing demand, EcoFlow is launching its OCEAN Pro energy storage system in the U.S., a grid-tied home backup battery compatible with rooftop solar systems. The product, which builds on EcoFlow’s success in Europe, promises 24/7 whole-home backup, AI-driven energy savings, and the ability to sell electricity back to the grid. The survey highlights a shifting energy landscape where consumers are actively seeking more trustworthy and effective alternatives to traditional energy providers and solutions.

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Other articles of interest in this TMIS eNewsletter for Summer 2025:

* Sustainable biodegradable products company has developed world’s first climate-positive, biodegradable cellulosic filament yarn engineered to replace polyester and nylon.

* AI conversational companion supports family and caregiver interactions with daily phone calls to seniors to help address the growing loneliness crisis.

* Public health campaign increases awareness and promotes preventive care on unprecedented scale through free posture screening and analysis using AI-powered digital billboard at public bus stops.

* New book, Shattering the Plastics Illusion, challenges common misconceptions about plastics with well-researched facts.

* Beauty and peril of vanishing glaciers takes center stage in global photography exhibition, urging climate action.

* Eye specialists encourage proactive response to evidence of early glaucoma, as waiting for symptoms to develop could result in lost vision.

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I am grateful to be in a collaborative business with many talented and skilled professionals. Your feedback is always welcome.

- Mary Michele McLaughlin


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